A new 'early-stage paper shows thats shedding happens with C19 vaccines.
There has been much discussion on shedding.
Due to personal observations, I believe it happens.
Many papers show scientists have been trying to make vaccines that spread, some with the excuse that this is the way to vaccinate wild populations of animals.
I have been mulling on the real reason the western Governments have pulled back on the vaccine drive.
We know they want 100% coverage.
They achieved 'vaccinating' about two thirds in the UK.
One reason that has crossed my mind is, had that achieved their goals? Was two thirds the critical mass they were after?
Does having two in every three people jabbed, mean that the other third will also be affected by the vaccine that is more accurately described as a bioweapon against the freewill of humanity?
Moreover as anyone who read the Pfizer leaked trial papers, would be forgiven for thinking that Pfizer themselves expected shedding.
This is a little reminder from that paper.
220.127.116.11. Exposure During Breastfeeding An exposure during breastfeeding occurs if:
A female is found to be breastfeeding while being exposed or having been exposed to study intervention (ie, environmental exposure). An example of environmental exposure during breastfeeding is a female family member or healthcare provider who reports that she is breastfeeding after having been exposed to the study intervention (trial participant) by inhalation or skin contact.
Are the findings in the paper below devalued by the paper not being peer reviewed?
2022 is the time of man where we have no time to wait for the authority of 'experts' to catch up and tick boxes.
We need peer review, and more importantly replication of these results,
however whilst the lumbering monster of official proof stumbles forwards, trying to dodge all industry attempts to derail it - it would be advisable for everyone to take heed and keep healthy.
Power up the immune system.
Become immune to fear
Destress the mind and body
Smile, dance and be happy
There are some useful tips and products here.
Evidence for Aerosol Transfer of SARS-CoV2-specific Humoral Immunity
(This paper has not been per reviewed)
Ross M. Kedl, PhD*,
Elena Hsieh, MD,
Thomas E. Morrison, PhD,
Gabriela Samayoa-Reyes, PhD,
Siobhan Flaherty, PhD,
Conner L. Jackson, PhD and
Rosemary Rochford, PhD.
Despite the obvious knowledge that infectious particles can be shared through respiration, whether other constituents of the nasal/oral fluids can be passed between hosts has surprisingly never even been postulated, let alone investigated. The circumstances of the present pandemic facilitated a unique opportunity to fully examine this provocative idea. The data we show provides evidence for a new mechanism by which herd immunity may be manifested, the aerosol transfer of antibodies between immune and non- immune hosts.
The vaccines against SARS-CoV-2 have maintained remarkable efficacy against severe disease and death in those vaccinated regardless of variant emergence, Omicron included 1 . Less appreciated than the systemic immunity generated by the vaccines are the high levels of antibody (IgG and IgA) found within the nasal cavity and saliva of vaccinees. This outcome is found in both humans and primates, and in response to both mRNA and protein-based vaccines 2,3. Respiratory transmission of viral infection is proof that oral/nasal cavity constituents can be communicated through aerosols and/or respiratory droplets. As such, it would stand to reason that antibody present within the oral/nasal environment may also be aerosolized to some degree.
A Multiplex Microsphere Immunoassay (MMIA) was constructed and performed as previously described 4. Under IRB # 20-1279, serum samples were obtained from first-responder adults in Arapahoe County, CO 5. Antibody was eluted 4 from punches taken from the center of surgical masks anonymously donated by laboratory workers.
Nasal swabs were obtained by convenience sampling both parents and their children at the Colorado Tricountry vaccine center in Aurora, CO who were attending vaccine appointments, not limited to SARS-CoV2. Antibody from swab tips was eluted as described for DBS 4.
The log transformed IgA and IgG values from the children’s samples were modeled using linear regression with a single binary covariate corresponding to high or low antibody levels from their parent. Residual plots were used to check violations of linear regression assumptions and a Wilcoxon rank sum test was conducted if assumptions were violated.
A linear mixed effects model was evaluated to assure that the correlation within household did not significantly contribute to the data or alter the conclusions drawn from the fixed effect linear regression model. Cytometry was performed using a Beckman Coulter Cytoflex cytometer and analyzed using FloJo v.10 software (Treestar, Inc.). Statistical analyses were conducted using R (version 4.0.2).
The extended mandates for mask wearing in both social and work environments provided a unique opportunity to evaluate the possibility of aerosolized antibody expiration from vaccinated individuals.
Utilizing a flow cytometry-based Multiplex Microsphere Immunoassay (MMIA) to detect SARS-CoV-2-specific antibodies (Fig 1A and B) 4,5 and a method previously used to elute antibody from rehydrated dried blood spots (DBS), we identified anti-SARS-CoV-2 specific antibodies eluted from surgical face masks worn by vaccinated lab members donated at the end of one workday.
Consistent with the results reported by others, we identified both IgG and IgA in saliva from vaccinated individuals (Fig 1C and D).
It was therefore not surprising to detect both IgG and IgA following elution of antibody from face masks (Fig 1C and D).
Given these observations, we hypothesized that droplet/aerosolized antibody transfer might occur between individuals, much like droplet/aerosolized virus particles can be exchanged by the same route.
To evaluate this hypothesis, we obtained nasal swabs from children living in households in which parents or family members had varying degrees of SARS-CoV2-specifc immunity, including those unvaccinated, vaccinated and COVID-19+. Initial comparison of nasal swabs acquired from children living in vaccinated households revealed readily detectable SARS-CoV-2-specific IgG (Fig 1E), especially when compared to the complete deficit of SARSCoV-2-specific antibody detected in the few nasal swabs we obtained from children in nonvaccinated households.
We then used the variation in parents’ levels of intranasal IgG as the basis of stratification across all children’s samples. Log transformation of the data from thirty four adult-child pairs established antibody cut-offs for high vs low parental intranasal antibody levels.
Evaluation of samples in this fashion revealed that high intranasal IgG in vaccinated parents was significantly associated (p-value = 0.01) with a 0.38 increase in the log transformed intranasal IgG gMFIs within a child from the same household (Fig 1F).
This significant positive relationship was observed using either parametric or non-parametric analysis, and adjustments for the correlation within household did not alter the conclusion.
Though not statistically significant, a similar trend of elevated IgA was found in the same samples.
↵Garcia-Beltran, W. F., St Denis, K. J., Hoelzemer, A., Lam, E. C., Nitido, A. D. et al. mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant. Cell 185, 457–466 e454, doi:10.1016/j.cell.2021.12.033 (2022). CrossRefPubMedGoogle Scholar
↵Corbett, K. S., Nason, M. C., Flach, B., Gagne, M., O’Connell, S. et al. Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates. Science 373, eabj0299, doi:10.1126/science.abj0299 (2021). AbstractGoogle Scholar
↵Nahass, G. R., Salomon-Shulman, R. E., Blacker, G., Haider, K., Brotherton, R. et al. Intramuscular SARS-CoV-2 vaccines elicit varying degrees of plasma and salivary antibody responses as compared to natural infection. medRxiv, 2021.2008.2022.21262168, doi:10.1101/2021.08.22.21262168 (2021). Abstract/FREE Full TextGoogle Scholar
↵Schultz, J. S., McCarthy, M. K., Rester, C., Sabourin, K. R., Annen, K. et al. Development and Validation of a Multiplex Microsphere Immunoassay Using Dried Blood Spots for SARS-CoV-2 Seroprevalence: Application in First Responders in Colorado, USA. J Clin Microbiol 59, doi:10.1128/JCM.00290-21 (2021). Abstract/FREE Full TextGoogle Scholar
↵Sabourin, K. R., Schultz, J., Romero, J., Lamb, M. M., Larremore, D. et al. Risk Factors of SARS-CoV-2 Antibodies in Arapahoe County First Responders-The COVID-19 Arapahoe SErosurveillance Study (CASES) Project. J Occup Environ Med 63, 191–198, doi:10.1097/JOM.0000000000002099 (2021). CrossRefPubMedGoogle Scholar
↵Hayek, S., Shaham, G., Ben-Shlomo, Y., Kepten, E., Dagan, N. et al. Indirect protection of children from SARS-CoV-2 infection through parental vaccination. Science, eabm3087, doi:10.1126/science.abm3087 (2022). CrossRefGoogle Scholar